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March
12, 2007 -- Green tea may fight lung cancer and could inspire the
creation of new lung cancer drugs, scientists report.
But it
may be too soon to count on a cup of green tea to curb lung cancer. So
far, the scientists have only tested green tea extract against human
lung cancer cells in test tubes, not people.
The
researchers included Qing-Yi Lu, PhD, of the Center for Human Nutrition
at the University of California at Los Angeles (UCLA).
Lu and
colleagues exposed a sample of human lung cancer cells to a
decaffeinated green tea extract. The lung cancer cells marinated in the
green tea extract for up to three days.
The
green tea extract remodeled a certain protein in the lung cancer cells.
As a result, the lung cancer cells became more likely to stick together
and less likely to move, the study shows.
Antioxidants in green tea may have tweaked the cancer cell protein, but
it's not clear whether one antioxidant deserves all the credit or
whether several antioxidants worked together, the researchers note.
The
study doesn’t prove that drinking green tea curbs lung cancer in people.
However, it may be possible to make new lung cancer drugs based on green
tea extract, Lu's team suggests. Such drugs would target the lung cancer
protein remodeled by the green tea extract in the lab tests.
The
study appears online in Laboratory Investigation.
SOURCES: Lu, Q. Laboratory Investigation, March 12, 2007; online
edition. News release, Laboratory Investigation.
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